Safety analysis of 2％ fusidic acid cream in multi-center treatment of bacterial skin disease

Objective To investigate the clinical efficacy and safety of 2％ fusidic acid cream in the treatment of bacterial skin disease.Methods Randomly selected 146 patients who were diagnosed as bacterial skin diseases in Xinye county people' s hospital from May 2010 to July 2013,they were randomly divided into experimental group and control group.In accordance with the principles of multi-center open experiment,the experimental group was taken 2 ％ fusidic acid cream,the control group was taken 2％ mupirocin ointment.And the treatment results of the two groups were analyzed.Results The total efficiency of the experimental group (95.9％) was significantly higher than that of control group (78.1％),the difference was significant(P ＜0.05).Adverse symptoms did not occur during the treatment in the experimental group,there were four patients had local burning and itching during treatment in control group,and the symptoms disappeared later.Conclusions Using 2％ fusidic acid cream in treating bacterial skin diseases has significant effect,it is safe and reliable,and it is recommended to be further promote in clinical practice. Key words: Bacterial skin diseases;  2％ fusidic acid cream;  Security