Observation on the effect of the integrative medicine in the treatment of gastrointestinal manifestations of Henoch-Schonlein purpura in children

Objective To investigate the clinical effect and safety of integrative medicine in treatment of gastrointestinal manifestations of Henoch-Schonlein purpura (HSP) in children.Methods 90 children with gastrointestinal manifestations of HSP were randomly divided into two groups,45 cases in each group.Control group was given hydrocortisone and prednisone,the treatment group was given self decoction of Chinese medicine on the basis of the control group.Clinical efficacy was observed after two courses.Results Total effective rate of the treatment group was 95.56％,which was higher than that of the control group(77.78％) (P ＜0.05).The disappearance time of HSP of the treatment group [(12.32 ± 3.59) d] was significantly shorter than that of the control group [(18.56 ± 4.18) d](P ＜ 0.05),and the incidence rate of adverse reactions has a significant reduction (4.44％ vs 11.11％,P ＜ 0.05).Conclusion Adjuvant treatment with Chinese medicine on the basis of western medicine in treatment of gastrointestinal manifestations of HSP in children,can significantly improve the clinical efficacy. Key words: Purpura, Henoch-Schonlein;  Child;  Glucocorticoids ;  Medicine, Chinese traditional