穆林菁, 楼善贤, 朱寿田, 刘庆伟
Abstract
目的 探讨胃肠道间质瘤(GISTs)的临床病理特点.方法应用常规病理及免疫组化观察87例GISTs,并复习相关文献.结果本组GISTs均为成年人,年龄28～73岁,平均53岁.发生于胃56例,小肠29例,结肠2例.镜下肿瘤由梭形细胞和上皮样细胞以不同的比例构成.瘤细胞Vimentin均阳性,CD117,CD34多为弥漫强阳性,SMA,S-100在肿瘤向平滑肌和神经方向分化时阳性.结论GISTs好发于中老年人,肿瘤由梭形细胞和上皮样细胞构成,免疫组化特征为CD117+,CD34+。
A significance statement is not available in the OpenAlex record.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
目的 探讨胃肠道间质瘤(GISTs)的临床病理特点.方法应用常规病理及免疫组化观察87例GISTs,并复习相关文献.结果本组GISTs均为成年人,年龄28～73岁,平均53岁.发生于胃56例,小肠29例,结肠2例.镜下肿瘤由梭形细胞和上皮样细胞以不同的比例构成.瘤细胞Vimentin均阳性,CD117,CD34多为弥漫强阳性,SMA,S-100在肿瘤向平滑肌和神经方向分化时阳性.结论GISTs好发于中老年人,肿瘤由梭形细胞和上皮样细胞构成,免疫组化特征为CD117+,CD34+。
Key concepts: Immunohistochemistry, Pathology, Stromal cell, Medicine