Effect of preemptive analgesia with dezocine on postoperative pain in gynaecological laparoscopic surgery

Objective To study the effect of preemptive analgesia intravenous injection with different doses of dezocine on postoperative pain after gynecological laparoscopic operation.Methods 120 female adult patients (the ASA Ⅰ-Ⅱ) who underwent the gynecological laparoscopic surgery were randomly divided into three groups.Patients in the group A were given physiological saline 5 ml before operation.Patients in the group B were given dezocine 0.1 mg/kg (diluted to 5 ml) before operation.Patients in the group C were given dezocine 0.2 mg/kg (diluted to 5 ml) before operation.Anesthesia induction and anesthesia contiue were the same.After returning to the anesthesia recovery room,the pain of incision was assessed by VAS and BCS scores at 2 h(T1),4 h(T2),8 h(T3) and 24 h(T4).When the VAS scores reached 8-10 and the BCS score was 0,patients were given 100 mg tramadol intramuscular injection.Records of the tramadol use time,number of cases,the intervals of tramadol.Results The VAS and BCS scores of patients at 2 h(T1),4h(T2),8 h(T3) and 24 h(T4) after reached the anesthesia recovery room,the experimental group was better than control group (P＜0.05).Postoperative tramadol group A greater than group B (P＜0.05),group B greater than group C (P＜0.05).The incidence of adverse reactions of the three groups had no statistical difference (P＞0.05).Conclusion Dezocine preemptive analgesia with 0.2 mg/kg can relieve pain in patients after gynecological laparoscopic operation,and increase satisfaction. Key words: Dezocine;  Gynecological laparoscopic surgery;  Preemptive analgesia