Observation of the clinical curative effect when adopt smoothing liver and invigorating spleen treatment to cure diarrhea-predominant irritable bowel syndrome

Objective To evaluate the clinical effects and safety when adopt smoothing liver and invigorating spleen treatment to cure diarrhea- predominant irritable bowel syndrome(D- IBS)characterized by liver stagnation with spleen deficiency. Methods 71 patients met the inclusion criteria of D- IBS were randomly divided into the treatment group(36 cases)and control group(35 cases), the treatment group used Shugan Jianpi therapy, traditional Chinese medicine Tongxieyao Fang and additive Shenlingbaishu Decoction; the control group taking Lactobacillus Complex Capsules treatment. Two groups of the time of taking medicine for 4 weeks.Observation and analysis of comprehensive effects and D- IBS symptom score before and after treatment. Results There was no statistical significance in the two groups before treatment, symptom total score difference, after the treatment group and the control group of symptom score were(4.83±3.30),(7.00±3.96), with a significant difference between the two groups(t= 2.51,P< 0.05); the total effective rate of treatment group was 91.67%, which was higher than 68.57% in the control group(χ2= 5.98,P< 0.05). Conclusion The adoption of the smoothing liver and invigorating spleen treatment characterized by the use of Tong Xie Yao Fang and additive Shen LingBaiZhu decoction to cure D- IBS patients with liver stagnation and spleen deficiency has a relatively satisfactory clinical curative effect. Key words: Smoothing liver and invigorating spleen treatment; Irritable bowel syndrome