Effect of reshuvastatin on hs-CRP and carotid atherosclerotic plaque in patients with acute cerebral infarction

Objective To analyze the changes of carotid atherosclerotic plaque and levels of serum high-sensitivity C-reactive protein (hs-CRP) in patients with acute cerebral infarction treated with risuvastatin were analyzed. Methods A total of 109 patients with acute cerebral infarction treated in the hospital from January 2016 to June 2017 were divided into two groups by random digital table, 54 cases in control group were treated with atorvastatin, and 55 cases in observation group were treated with rosuvastatin. The changes of hs-CRP, blood lipid and carotid atherosclerotic plaque thickness were compared between the two groups after treatment. Results After treatment, total cholesterol (TC), triglycerides (TG), low-density lipoprotein (LDL-C), hs-CRP and carotid atherosclerotic plaque thickness of the observation group were lower than those of the control group (P<0.05). Conclusions Resuvastatin can effectively reduce inflammatory factors and blood lipid levels in patients with acute cerebral infarction and reverse atherosclerotic plaque. Key words: Reshuvastatin; Acute cerebral infarction; High sensitivity C-reactive protein; Carotid atherosclerotic plaque