The Clinical Significance of Serum High-sensitivity C-reactive Protein in Diabetic Patients with Atherosclerotic Cerebral Infarction

Objective To investigate the changes of serum high-sensitivity C-reactive protein(hs-CRP)in type 2 diabetic patients with atherosclerotic cerebral infarction.Methods The patients were diagnosed atherosclerotic cerebral infarction.The experimental group of 26 patients with diabetes and the control group were 83 cases of non-diabetic patients.Dry-type quantitative immunofluorescence method was used for the determination of the concentration of serum hs-CRP.We used vitro diagnostic kit for determination of blood lipids,blood sugar level,and carotid color Doppler to check the carotid atherosclerotic plaque size and ultrasound characteristics,simultaneously the changes of carotid artery intima-media thickness(IMT).Results The hs-CRP levels in the experimental group was significantly higher than in control group,the difference was statistically significant(P0.05);IMT and the occurred cases of plaque which more than two grade were more than the control group,The difference was statistically significant(P0.05).Conclusion Serum hs-CRP has important predictive value in the genesis,development and prognosis of diabetic patients with atherosclerotic cerebral infarction.