2002•Unpublished venueRequires access

The clinical contrast study of determining glomerular filtration rate by calculation and using clearance rate of99mTc-DTPA

吴锡信, 陈江林, Jian Zhong Peng

Abstract

目的评价临床应用计算法测定肾小球滤过率(GFR)的准确性.方法用99mTc-DTPA清除率测定60例不同疾病住院病人GFR(Tc-GFR),并测血清肌酐,同时以WCP公式测定GFR(WCP-GFR),以Cockcroft/Gault公式计算内生肌酐清除率(CG-CCr).肾功能不全及正常组WCP-GFR、CG-GFR分别与Tc-GFR进行相关分析,比较两组WCP-GFR、CG-GFR与Tc-GFR间显著性差异以及WCP-GFR、Tc-GFR间平均差和CG-GFR、Tc-GFR间平均差的显著性差异.结果 WCP-GFR及CG-CCr均可在一定程度上准确反映GFR,而以WCP-GFR数值更接近Tc-GFR,准确性更高,临床上可代替Tc-GFR.结论 WCP-GFR是一种准确、简便、快捷测定GFR方法.

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Key concepts: Contrast (vision), Renal function, Clearance, Medicine, Filtration (mathematics), Mathematics, Internal medicine, Statistics