Comparative study of determining glomerular filtration rate by the calculation method

Objective To probe the clinical value of determining glomerular filtration rate(GFR) by the calculation method.Methods GFRs from 106 cases in hospital suffering from the different diseases were determined accurately by using Clearance rate of ~(99m) Tc-DTPA(Tc-GFR),and the serum creatinine and blood urea nitrogen were determined and GFRs were calculated simultaneously by WCP formula and Robert formula(WCP-GFR,Robert-GFR) and clearance rate of creatinine was calculated by Cockcroft/Gault formula(CG-CCr).Comparative study and relative analysis were done for all the data.Results WCP-GFR and Robert-GFR and CG-CCr could all give expression to GFR accurately to some extent,and WCP-GFR was more accurate than others and could take the place of Tc-GFR clinically.Conclusion WCP-GFR was an accurate,simple,fast,safe and cheap method for determining GFR and should be applied widely.