ScholarLens Back to search
2001•Unpublished venueRequires access

The observation of DNA damage caused by HT-2 toxin with SCGE

卜黎明, 程绍辉, Ning Liu, 姚红菊, 孙殿军

Open publisher page 0 citations

Abstract

Objective To detect the DNA damage of Hela cells caused by HT-2toxin.Methods We conducted this study with MTT and Single Cell Gel Electrophoresis (SCGE).Results The results showed that HT-2 toxin can damage the cell DNA,and the dose-effect relationship is founded that with the dose increasing (800 ng/ml to 1600 ng/ml),the degree of DNA damage is increasing,the tail length are (28.4±5.67)μm and (55.8±10.47)μm,respectively.Conclusions HT-2 toxin can cause the cell DNA damage.

About this research paper

What this paper is about

Objective To detect the DNA damage of Hela cells caused by HT-2toxin.Methods We conducted this study with MTT and Single Cell Gel Electrophoresis (SCGE).Results The results showed that HT-2 toxin can damage the cell DNA,and the dose-effect relationship is founded that with the dose increasing (800 ng/ml to 1600 ng/ml),the degree of DNA damage is increasing,the tail length are (28.4±5.67)μm and (55.8±10.47)μm,respectively.Conclusions HT-2 toxin can cause the cell DNA damage.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To detect the DNA damage of Hela cells caused by HT-2toxin.Methods We conducted this study with MTT and Single Cell Gel Electrophoresis (SCGE).Results The results showed that HT-2 toxin can damage the cell DNA,and the dose-effect relationship is founded that with the dose increasing (800 ng/ml to 1600 ng/ml),the degree of DNA damage is increasing,the tail length are (28.4±5.67)μm and (55.8±10.47)μm,respectively.Conclusions HT-2 toxin can cause the cell DNA damage.

Key concepts: DNA damage, DNA, HeLa, Toxin, Gel electrophoresis, Molecular biology, Chemistry, Cell

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
The observation of DNA damage caused by HT-2 toxin with SCGE — Research Paper | ScholarLens