Different infusion methods of propofol in the anesthesia for the aged more than 80 years during painless colonoscopy

Objective To investigate the results of three formula of anesthesia management of propofol in the aged more than 80 years during colonoscopy. Methods 120 aged patients＞80 years scheduled to undergo painless colonoscopy were randomly divided into three groups,Group Ⅰ,Ⅱ and Ⅲ,each group 40 patients.Patients in Group Ⅰ received target controlled infusion of propofol and in Group Ⅱ received continuous infused propofol by vein pump,while patients in Group Ⅲ received manual controlled infusion of propofol.MAP、ECG、HR、SpO2 were recorded before colonoscopy,during and after colonoscopy.Anesthetic induction time,length of colonoscopy time,total propofol dosage,recovery time,side effects and satisfaction were also recorded. Results All patients had finished colonoscopy safely.There is no difference about MAP,ECG,HR and SpO2 among the three groups.The anesthetic induction time were (40±6),(58±10),(58±8) s,respectively.The recovery time were (3.7±1.3),(5.0±1.8),(6.9±1.7)min,respectively.The total propofol dosage were (91±11), (1 10±14), (131±16) mg,respectively.In Group Ⅰ,lower propofol dosage was recorded,anesthetic induction time and recovery time were shorter than those in Group Ⅱ and Ⅲ.The side effects were the least in Group Ⅰ and its satisfaction was the best. Conclusions It is satisfactory in aged patients＞80 years to administer propofol with different administration ways during colonoscopy.Target controlled infusion (TCL) of propofol may be the better way for the anesthesia ofthe aged during painless colonoscopy. Key words: The aged＞80 years;  Painless colonoscopy;  Propofol;  Target controlled infusion