2012•国际移植与血液净化杂志Requires access

Clinical analysis patients with acute paraquat poisoning

Ming-qian Luo, Cui-hua Xian, Xiaofeng Shi, Ye-juan Zhong, Hui-jie Xuan

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Abstract

Objective To analysis clinical characteristics of the patients with acute paraquat poisoning,find strategies to reduce the mortality rate.Method A total of 14 patients subjected to acute paraquat poisoning admitted from January 2008 to January 2012 were retrospectively studied.Results The mortality was 64%(9 cases),and survival time ranged from 40 h to 175 h.7 cases died in hospitals,2 cases die at home,and all of them died from multiorgan failure.5 cases who were given gave emetic,gastric lavage,catharsis and symptomatic treatment survived.4 cases of survivors were complicated with non oliguria acute renal failure.Conclusion The patients with acute paraquat poisoning should be given emetic,gastric lavage and catharsis as soon as possible to reduce absorption of the toxic chemical after poisoning.Blood purification and immunosuppressive therapy had no remarkable superiority in decreasing mortality of critical patients. Key words: Paraquat; Poisoning; Prognosis; Prevention

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Objective To analysis clinical characteristics of the patients with acute paraquat poisoning,find strategies to reduce the mortality rate.Method A total of 14 patients subjected to acute paraquat poisoning admitted from January 2008 to January 2012 were retrospectively studied.Results The mortality was 64%(9 cases),and survival time ranged from 40 h to 175 h.7 cases died in hospitals,2 cases die at home,and all of them died from multiorgan failure.5 cases who were given gave emetic,gastric lavage,catharsis and symptomatic treatment survived.4 cases of survivors were complicated with non oliguria acute renal failure.Conclusion The patients with acute paraquat poisoning should be given emetic,gastric lavage and catharsis as soon as possible to reduce absorption of the toxic chemical after poisoning.Blood purification and immunosuppressive therapy had no remarkable superiority in decreasing mortality of critical patients. Key words: Paraquat; Poisoning; Prognosis; Prevention

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Available abstract

Objective To analysis clinical characteristics of the patients with acute paraquat poisoning,find strategies to reduce the mortality rate.Method A total of 14 patients subjected to acute paraquat poisoning admitted from January 2008 to January 2012 were retrospectively studied.Results The mortality was 64%(9 cases),and survival time ranged from 40 h to 175 h.7 cases died in hospitals,2 cases die at home,and all of them died from multiorgan failure.5 cases who were given gave emetic,gastric lavage,catharsis and symptomatic treatment survived.4 cases of survivors were complicated with non oliguria acute renal failure.Conclusion The patients with acute paraquat poisoning should be given emetic,gastric lavage and catharsis as soon as possible to reduce absorption of the toxic chemical after poisoning.Blood purification and immunosuppressive therapy had no remarkable superiority in decreasing mortality of critical patients. Key words: Paraquat; Poisoning; Prognosis; Prevention

Key concepts: Medicine, Paraquat, Gastric lavage, Oliguria, Mortality rate, Acute toxicity, Surgery, Internal medicine

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Clinical analysis patients with acute paraquat poisoning — Research Paper | ScholarLens