Effects of insulin pump continuous subcutaneous injection on blood glucose and pregnancy outcome in patients with gestational diabetes mellitus

Objective To analyze the effect of continuous subcutaneous injection of insulin pump on gestational diabetes mellitus (GDM) and its influence on pregnancy outcome. Methods A total of 78 patients with GDM in Zaozhuang Maternal and Child Health Hospital from January 2018 to November 2018 were selected and divided into observation group (n=39) and control group (n=39) by random number table method. The control group received routine subcutaneous injection of insulin, and the observation group received continuous subcutaneous injection of insulin pump. The blood glucose indexes, including fasting blood glucose (FBG), glycosylated hemoglobin (HbAlc), 2 h postprandial blood glucose (2hPBG), and pregnancy outcomes were compared between the two groups. Results The levels of FBG, HbAlc and 2hPBG in the two groups after treatment were lower than those before treatment, and those in the observation group were lower than those in the control group, with statistically significant differences (P<0.05). The incidence rates of neonatal asphyxia, maternal hypoglycemia, postpartum infection, premature infants, gestational hypertension and neonatal hyperbilirubinemia were lower in the observation group than the control group, with statistically significant differences (P<0.05). Conclusions Continuous subcutaneous injection of insulin pump for GDM patients can control blood sugar level better, which is conducive to optimizing pregnancy outcome and is of great significance for the maintenance of maternal and infant health. Key words: Gestational diabetes mellitus; Insulin pump; Continues subcutaneous injection; Blood glucose; Pregnancy outcomes