Study of serum sialic acidclinical significance in malignant tumor

：Objective To study thediagnosis value and clinical significance of serum sialic acid in malignant tumor. MethodsUsing enzymic method, the serum sialic acid levels were detected in 50 healthy persons, 90benign disease patients, 160 malignant tumor patients. The serum sialic acid levels changewere analyzed in different pathological types and after relative treatment. Results Theserum sialic acid levels and positive ratio in malignant tumor groups were apparentlyhigher than those in normal control and benign disease groups (P 0.05). The serum sialicacid levels in the improved patients significantly dropped (P <0.01), while those inthe aggravated patients had an ascendent tendency.Conclusion The serum sialic acid hassignificant value in diagnosis, therapeutic effect and prognosis of malignant tumor.