Clinical value of serum sialic acid in the diagnosis of malignant tumors of women

Objective To investigate the clinical value of serum sialic acid in the diagnosis of malignant tumors in women. Methods 225 cases of female patients with malignant tumor treated in our hospital were selected as malignant tumor group, 169 cases of healthy women were selected as the control group during the same period, and150 cases of healthy women during menses were evolved in menstrual period group. The serum sialic acid levels of all cases were detected with LX20 automatic biochemical analyzer produced by USA Backman company. The levels of serum sialic acid in different groups were compared. Results The serum sialic acid in malignant tumor group was(87.4±13.2) mg/dl, which was significantly higher than that in the control group and the menstrual period group(P0.05). There was no significant difference between control group and menstrual period group in the value of serum sialic acid(P0.05). There were 157 positive cases and 68 negative cases in malignant tumor group, the positive rate in which was significantly higher than that in control group and the menstrual period group(P0.05), while there was no significant difference in the positive rate between the control group and the menstrual period group(P0.05). In malignant tumor group, there were no significant differences in the serum sialic acid levels between different pathological types.(P0.05). Conclusion The level of serum sialic acid increases in woman with malignant tumor, which has important clinical value in evaluation and prognosis of that disease.