Detection methods and clinical applications of circulating tumor cells in breast cancer
Yujie Wang, Xia Guo, Xiaofei Wang
Abstract
Yujie Wang, Xia Guo, Xiaofei Wang
Abstract
Early metastasis of breast cancer and recurrence is proved to be the greatest threat to the patients. The detection of circulating breast tumor cells in blood is an important evidence of tumor micrometastasis. Current detection methods of circulating tumor cells including antibody based technique, nucleic acid based technique and the joint detection methods. All of them have their advantages and limitations. Key words: Circulating tumor cells; Breast cancer; Micrometastasis
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Early metastasis of breast cancer and recurrence is proved to be the greatest threat to the patients. The detection of circulating breast tumor cells in blood is an important evidence of tumor micrometastasis. Current detection methods of circulating tumor cells including antibody based technique, nucleic acid based technique and the joint detection methods. All of them have their advantages and limitations. Key words: Circulating tumor cells; Breast cancer; Micrometastasis
Key concepts: Micrometastasis, Circulating tumor cell, Breast cancer, Metastasis, Medicine, Cancer, CA15-3, Metastatic breast cancer