2019•国际医药卫生导报Requires access

Risk factors of rebleeding after surgery for hypertensive intracerebral hemorrhage and its countermeasures

Wu-feng Luo, Yingbiao Hong, Jiebo Cai, Chen Ze-xin, Yuehao Cai, Guangjun Huang

Open publisher page 0 citations

Abstract

Objective To discuss the coherent risk indicators of re-bleeding after the first operation for cerebral hemorrhage caused by spontaneous vascular hypertension, and to reduce the risk of rebleeding taking some countermeasures corresponding to the relevant risk factors. Methods 130 patients with cerebral hemorrhage caused by spontaneous vascular hypertension treated at the department of neurology of our hospital were randomly selected as study objects, and were surgically treated and divided into a rebleeding group and a control group. The clinical data of the two groups were compared. The risk factors of rebleeding on the first operation sites were analyzed. Results The incidence of rebleeding on surgical sites after the first operation due to various factors was 9.23%. The head CT scan showed that the rebleeding sites were located in the original surgical area, and the mortality of rebleeding patients reached 59.68%. In patients with spontaneous angiogenic hypertensive intracerebral hemorrhage, postoperative local rebleeding positively correlated with the first operation time after hemorrhage, coagulation factor loss or poor coagulopathy, postoperative mean value of systolic blood pressure detected by NICU or ICU, and the degree of postoperative agitation (all P 0.05). Logistic regression equation was used to analyze all possible related risk factors, and the results showed that the coagulation dysfunction caused by acute onset to first surgery intervention, clotting factor loss or poor, and the mean postoperative systolic blood pressure detected by NICU were the independent risk factors for postoperative rebleeding on the surgical sites (all P<0.05). Conclusion Mastering the time of initial surgery after cerebral hemorrhage, good management of postoperative blood pressure, correcting possible coagulopathy, and avoiding postoperative irritability can significantly reduce the chance of recurrent bleeding after initial surgery for spontaneously hypertensive cerebral hemorrhage. Key words: Hypertensive cerebral hemorrhage; Rebleeding; Risk factors; Countermeasures

About this research paper

What this paper is about

Objective To discuss the coherent risk indicators of re-bleeding after the first operation for cerebral hemorrhage caused by spontaneous vascular hypertension, and to reduce the risk of rebleeding taking some countermeasures corresponding to the relevant risk factors. Methods 130 patients with cerebral hemorrhage caused by spontaneous vascular hypertension treated at the department of neurology of our hospital were randomly selected as study objects, and were surgically treated and divided into a rebleeding group and a control group. The clinical data of the two groups were compared. The risk factors of rebleeding on the first operation sites were analyzed. Results The incidence of rebleeding on surgical sites after the first operation due to various factors was 9.23%. The head CT scan showed that the rebleeding sites were located in the original surgical area, and the mortality of rebleeding patients reached 59.68%. In patients with spontaneous angiogenic hypertensive intracerebral hemorrhage, postoperative local rebleeding positively correlated with the first operation time after hemorrhage, coagulation factor loss or poor coagulopathy, postoperative mean value of systolic blood pressure detected by NICU or ICU, and the degree of postoperative agitation (all P 0.05). Logistic regression equation was used to analyze all possible related risk factors, and the results showed that the coagulation dysfunction caused by acute onset to first surgery intervention, clotting factor loss or poor, and the mean postoperative systolic blood pressure detected by NICU were the independent risk factors for postoperative rebleeding on the surgical sites (all P<0.05). Conclusion Mastering the time of initial surgery after cerebral hemorrhage, good management of postoperative blood pressure, correcting possible coagulopathy, and avoiding postoperative irritability can significantly reduce the chance of recurrent bleeding after initial surgery for spontaneously hypertensive cerebral hemorrhage. Key words: Hypertensive cerebral hemorrhage; Rebleeding; Risk factors; Countermeasures

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To discuss the coherent risk indicators of re-bleeding after the first operation for cerebral hemorrhage caused by spontaneous vascular hypertension, and to reduce the risk of rebleeding taking some countermeasures corresponding to the relevant risk factors. Methods 130 patients with cerebral hemorrhage caused by spontaneous vascular hypertension treated at the department of neurology of our hospital were randomly selected as study objects, and were surgically treated and divided into a rebleeding group and a control group. The clinical data of the two groups were compared. The risk factors of rebleeding on the first operation sites were analyzed. Results The incidence of rebleeding on surgical sites after the first operation due to various factors was 9.23%. The head CT scan showed that the rebleeding sites were located in the original surgical area, and the mortality of rebleeding patients reached 59.68%. In patients with spontaneous angiogenic hypertensive intracerebral hemorrhage, postoperative local rebleeding positively correlated with the first operation time after hemorrhage, coagulation factor loss or poor coagulopathy, postoperative mean value of systolic blood pressure detected by NICU or ICU, and the degree of postoperative agitation (all P 0.05). Logistic regression equation was used to analyze all possible related risk factors, and the results showed that the coagulation dysfunction caused by acute onset to first surgery intervention, clotting factor loss or poor, and the mean postoperative systolic blood pressure detected by NICU were the independent risk factors for postoperative rebleeding on the surgical sites (all P<0.05). Conclusion Mastering the time of initial surgery after cerebral hemorrhage, good management of postoperative blood pressure, correcting possible coagulopathy, and avoiding postoperative irritability can significantly reduce the chance of recurrent bleeding after initial surgery for spontaneously hypertensive cerebral hemorrhage. Key words: Hypertensive cerebral hemorrhage; Rebleeding; Risk factors; Countermeasures

Key concepts: Medicine, Intracerebral hemorrhage, Hemostasis, Spontaneous intracerebral hemorrhage, Logistic regression, Risk factor, Surgery, Blood pressure

Related papers

Back to paper searchBrowse research topicsOriginal source
Risk factors of rebleeding after surgery for hypertensive intracerebral hemorrhage and its countermeasures — Research Paper | ScholarLens