2007Chinese Journal of Clinical HepatologyRequires access

Relationship between serum HBV DNA levels and serum hyaluronic acid levels in hepatitis B cirrhosis patients

李红艺, 董忠, 马红

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Abstract

目的 研究乙肝肝硬化患者血清HBV DNA水平和血清透明质酸的关系.方法 临床确诊为乙肝肝硬化的62例患者,采用荧光定量PCR检测血清HBV DNA水平,放射免疫法检测血清透明质酸,对血清HBV DNA水平和透明质酸的关系进行研究分析.结果 乙肝肝硬化患者的血清透明质酸水平显著升高,随Child分级的加重血清透明质酸也呈增高趋势(P<0.05),但与血清HBV DNA水平差异无统计学意义(P>0.05).结论 乙肝肝硬化患者的血清HBV DNA和肝硬化的程度及血清透明质酸水平无显著相关性。

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目的 研究乙肝肝硬化患者血清HBV DNA水平和血清透明质酸的关系.方法 临床确诊为乙肝肝硬化的62例患者,采用荧光定量PCR检测血清HBV DNA水平,放射免疫法检测血清透明质酸,对血清HBV DNA水平和透明质酸的关系进行研究分析.结果 乙肝肝硬化患者的血清透明质酸水平显著升高,随Child分级的加重血清透明质酸也呈增高趋势(P<0.05),但与血清HBV DNA水平差异无统计学意义(P>0.05).结论 乙肝肝硬化患者的血清HBV DNA和肝硬化的程度及血清透明质酸水平无显著相关性。

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Available abstract

目的 研究乙肝肝硬化患者血清HBV DNA水平和血清透明质酸的关系.方法 临床确诊为乙肝肝硬化的62例患者,采用荧光定量PCR检测血清HBV DNA水平,放射免疫法检测血清透明质酸,对血清HBV DNA水平和透明质酸的关系进行研究分析.结果 乙肝肝硬化患者的血清透明质酸水平显著升高,随Child分级的加重血清透明质酸也呈增高趋势(P<0.05),但与血清HBV DNA水平差异无统计学意义(P>0.05).结论 乙肝肝硬化患者的血清HBV DNA和肝硬化的程度及血清透明质酸水平无显著相关性。

Key concepts: Hyaluronic acid, Cirrhosis, Hepatitis B, Medicine, Gastroenterology, Hepatitis B virus, Internal medicine, Hepatitis

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