The anesthesia effect of propofol and sevoflurane in the operation of elderly patients

Objective To study the anesthesia effect of propofol and sevoflurane in the operation of elderly patients, analyze the advantages and disadvantages of two anesthesia drugs, and explore the best anesthesia method for elderly patients. Methods 60 elderly patients treated in our hospital from September 2013 to September 2015 were selected, and randomly and equally divided into two groups. Sevoflurane group underwent induced anesthesia of sevoflurane and injection of remifentanil, propofol group underwent continuous injection of remifentanil and injection of propofol. HR, MAP, and the blood gas analysis (pH, PO2, PCO2) were compared between two groups before surgery (T0), 10 min after the beginning (T1), 30 min after the beginning (T2), 30 min before the end (T3), 10 min before the end (T4). The postoperative recovery was observed. Results HR and MAP at T2 and T3 were lower than those at T1 in two groups, HR and MAP at T2 in sevoflurane group were (73.89±7.13) times/min, (80.69±9.43) mmHg, those at T3 were (72.11±6.25) times/min, (80.14±8.91) mmHg, HR and MAP at T2 in propofol group were (66.24±7.24) times/min, (68.71±10.18) mmHg, those at T3 were (63.47±6.45) times/min, (67.13±11.35) mmHg, HR and MAP at T2 and T3 in propofol group were lower than those in sevoflurane group, with statistically significant differences between two groups (P 0.05). Conclusion For elderly patients, the combined anesthesia of sevoflurane has better effect compared with propofol. During the operation, patients’ vital signs are more stable, the awakening time greatly shortens, worthy of clinical promotion. Key words: Propofol; Sevoflurane; Elderly; Operation; Anesthesia