Comparison between Propofol and Sevoflurane during Operation with Suspension Laryngoscopy

Objective To compare propofol with sevoflurane with remifentanil target-controlled infusion(TCI) respectively during operation of suspension laryngoscopy.Methods Forty ASA Ⅰ-Ⅱ patients scheduled for the vocal cord surgery through suspension laryngoscopy were randomly divided into two groups:Propofol group(P group) and Sevoflurane group(S group),20 cases in each.Both groups were induced with intravenous midazolam 1.0～1.5 mg,succinylcholine 1.5～2.0 mg/kg and remifentanil 4 μg/L in TCI.P group was induced with Propofol 3 μg/ml in TCI and S group with intravenous propofol 1.5～2.0 mg/kg.After intubation,patients in S group inhaled 2%～4% sevoflurane to get sevoflurane concentration to 1 MAC,and combined with remifentanil in TCI.Patients in P group were maintained with remifentanil and propofol in TCI.HR and MAP at different time point,waking time,extubation time and side effects were recorded and compared.Results In both groups after induction,the HR at T1(1 min after induction) declined as compared with T0(before operation)(P0.05),and MAP at T1 and T2(1 min after intubation) declined as compared with T0(P0.05).But HR in P group at T1,T2 and T7(operation finished) declined more significantly than that in S group(P0.05).While waking time and extubation time in S group were shorter than in P group(P0.05).Conclusion Both methods of anaethesia can achieve good effect in the suspension laryngoscopy,but the patients maintained with sevoflurane had more stable hemodynamics and recovered sooner.