Effects of Qingfei Zhike Dingchuan ointment combined with azithromycin on mycoplasma pneumonia and their influence on serum inflammatory factors

Objective To investigate the curative effect of Qingfei Zhike Dingchuan ointment(QZDO)combined with azithromycin in treating mycoplasma pneumonia and its influence on serum inflammatory factors. Methods The 80 patients with pediatric mycoplasma pneumonia were selected from Linqu Hospital of Chinese Medicine from September 2013 to March 2015.The patients were randomly divided into control group and observation group, with 40 patients in each group.Children of the two groups received symptomatic and supportive treatment.Control group were given azithromycin treatment, while observation group were given QZDO combined with Azithromycin.Clinical effect, the changes of the frequece of Th17 cells of the patient and serum levels of IL-17 and IL-6 were meafured. Results The effective rate of observation group was 95%, significantly higher than that of the control group(80%). The difference was statistically significant(P 0.05). While the observation group patients exhibited substantially lower level of the Th17 cells, serum IL-17 and IL-116 than that of the control group after treatment(P<0.05). Conclusion The combination of QZDO with azithromycin for the treatment of Mycoplasma Pneumonia can improve clinical efficiency, and reduce Th17 and inflammatory cytokines levels. Key words: Mycoplasma Pneumonia; Qingfei Zhike Dingchuan ointment; Azithromycin; Serum inflammatory factors