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Osteopontin-related signal pathways and tumor metastasis

陈荣新, 叶胜龙

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Abstract

骨桥蛋白(osteopontin OPN)是一种具有多种功能的细胞外基质蛋白.OPN与其受体(整合素或CD44V)结合后激活细胞内多条信号通路,参与肿瘤转移的多个过程.本文综述OPN相关信号通路促进肿瘤转移的研究.

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What this paper is about

骨桥蛋白(osteopontin OPN)是一种具有多种功能的细胞外基质蛋白.OPN与其受体(整合素或CD44V)结合后激活细胞内多条信号通路,参与肿瘤转移的多个过程.本文综述OPN相关信号通路促进肿瘤转移的研究.

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Available abstract

骨桥蛋白(osteopontin OPN)是一种具有多种功能的细胞外基质蛋白.OPN与其受体(整合素或CD44V)结合后激活细胞内多条信号通路,参与肿瘤转移的多个过程.本文综述OPN相关信号通路促进肿瘤转移的研究.

Key concepts: Osteopontin, Metastasis, Medicine, Cancer research, Cancer, Internal medicine

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