2012白血病·淋巴瘤Requires access

Development of cytokine-induced killer cells in hematological oncology

Xinyu Yang

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Abstract

Cytokine-induced killer ( CIK ) cells are a cluster of heterogeneous cells prepared from human peripheral blood mononuclear cells ( PBMC ) with the co-stimulation of some kinds of cytokines.CIK cells are characterized with rapid proliferation rate, high antitumor effects, broad tumoricidal spectrum, and few side effects.CIK cells have particularly applied in hematology.Now it starts a new generation of adoptive immunotherapy.In this article new development of CIK cells in department of hematology is reviewed. Key words: Cytokine-induced killer cells;  Dendritic cell;  Hematologic neoplasms

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What this paper is about

Cytokine-induced killer ( CIK ) cells are a cluster of heterogeneous cells prepared from human peripheral blood mononuclear cells ( PBMC ) with the co-stimulation of some kinds of cytokines.CIK cells are characterized with rapid proliferation rate, high antitumor effects, broad tumoricidal spectrum, and few side effects.CIK cells have particularly applied in hematology.Now it starts a new generation of adoptive immunotherapy.In this article new development of CIK cells in department of hematology is reviewed. Key words: Cytokine-induced killer cells;  Dendritic cell;  Hematologic neoplasms

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Available abstract

Cytokine-induced killer ( CIK ) cells are a cluster of heterogeneous cells prepared from human peripheral blood mononuclear cells ( PBMC ) with the co-stimulation of some kinds of cytokines.CIK cells are characterized with rapid proliferation rate, high antitumor effects, broad tumoricidal spectrum, and few side effects.CIK cells have particularly applied in hematology.Now it starts a new generation of adoptive immunotherapy.In this article new development of CIK cells in department of hematology is reviewed. Key words: Cytokine-induced killer cells;  Dendritic cell;  Hematologic neoplasms

Key concepts: Hematology, Cytokine-induced killer cell, Peripheral blood mononuclear cell, Cytokine, Immunology, Immunotherapy, Medicine, Adoptive immunotherapy

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