Advance in Elementary Research of Cytokine-induced Killer Cells
WU Chang-pin
Abstract
WU Chang-pin
Abstract
Cytokine-induced killer(CIK)cells are a cluster of alloplasm cells,which are prepared from the mononuclear cells of human peripheral blood that might be stimulated by some kinds of cytokines.The proliferation and cytotoxicity of CIK cells are high,and the side effect is low.CIK cell is a more effective anti-tumor effector cell in adoptive immunotherapy.This article reviewed the biological features,anti-tumor activity and other elementary research of CIK cells.
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Cytokine-induced killer(CIK)cells are a cluster of alloplasm cells,which are prepared from the mononuclear cells of human peripheral blood that might be stimulated by some kinds of cytokines.The proliferation and cytotoxicity of CIK cells are high,and the side effect is low.CIK cell is a more effective anti-tumor effector cell in adoptive immunotherapy.This article reviewed the biological features,anti-tumor activity and other elementary research of CIK cells.
Key concepts: Cytokine-induced killer cell, Peripheral blood mononuclear cell, Adoptive immunotherapy, Cytokine, Immunology, Lymphokine-activated killer cell, Cytotoxicity, Effector