Bacterial culture and drug sensitivity of eye secretions in 1 482 infants with dacryocystitis

Objective To investigate the distribution of bacteria and drug sensitivity of eye secretions in infants with dacryocystitis. Methods The data of 1 482 infants with dacryocystitis were collected from Apr. 2016 to Apr. 2018. The bacterial culture, drug sensitivity and drug resistance were analyzed on eye secretions. Results The pathogenic bacteria were detected in 1 031 strains, the positive rate was 69.57%. There were 707 strains of gram-positive cocci, accounting for 68.57%. Staphylococcus aureus, Streptococcus pneumoniae, and Streptococcus pneumoniae were mainly pathogenic bacteria. The resistance of Zoxicillin, Penicillin and Ampicillin were the highest. The sensitivity to teicoplanin and vancomycin was the highest. There were 311 strains(30.16%) of gram-negative bacilli. Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa were mainly pathogenic bacteria, and the resistance rate of compound new noxamine, ampicillin and gentamicin was high, the sensitivity of three generation cephalosporins was high, and the highest sensitivity was imipenem and meropenem. There were 6 strains(0.58%) of gram-positive bacilli, 5 strains(0.48%) of gram- negative cocci and 2 strains(0.19%) of fungi. Conclusion The antibiotics should be selected rationally according to the drug sensitivity test results of the pathogenic bacteria isolated from the eye secretions of dacryocystitis, which can avoid misuse and blind drug use, so as to ensure the rational, safe and effective drug use of the children. Key words: Dacryocystitis; Infant; Bacterial culture; Drug sensitivity; Analysis