Distribution and drug susceptibility of pathogenic bacteria in 1 287 cases of neonatal dacryocystitis

Objective To analyze the distribution of pathogenic bacteria and drug susceptibility results in 1 287 cases of neonatal dacryocystitis in Henan Province. Methods Retrospective analysis.The pathogen culture and drug susceptibility results of 1 287 cases of dacryocystorhin in this hospital from Jan.2018 to Dec.2018 were collected. Results A total of 1 099 pathogenic bacteria were detected, and the detection rate was 85.4%.There were 618 Gram-positive bacteria strains (56.2%), included Staphylococcus aureus (19.3%), Staphylococcus epidermidis (17.5%), Streptococcus mutans (10.4%). There were 458 Gram-negative bacteria strains (41.7%), included Haemophilus influenzae (17.0%), Escherichia coli (11.5%), Klebsiella pneumoniae (7.4%). There were 23 fungi strains (2.1%). Gram-positive bacteria was the most sensitive to Vancomycin (98.8%), followed by levofloxacin (92.4%). Gram-negative bacteria was the most sensitive to imipenem (96.1%), followed by ciprofloxacin (91.4%). The resistance rate of Gram-positive bacteria and Gram-negative bacteria was the highest for erythromycin. Conclusion Gram-positive bacteria are higher than Gram-negative bacteria in the pathogenic bacteria of neonatal dacryocystitis. Key words: Dacryocystitis, neonatal; Bacteria, pathogenic; Sensitivity, drug