Distribution and drug resistance of bacteria from eye secretions of 339 infants

Objective:To study distribution of bacteria in infants eye infection and restistance to commonly used antimicrobial drugs,so as to proivide the evidence for clinical rational use of antimicrobial agents.Methods: Bacteria culture and drug susceptibility test were carried out on eye secretions from 339 suspected ophthalmia patients,and the results were analyzed retrospectively.Results: Among 339 bacteria culture specimens,bacterial growth were found in 119 cases(35.10%);121 pathogenic strains were isolated,including 68 gram-positive bacteria strains(68/121,56.20%,most were staphylococcus aureus and coagulase negative staphylococcus,high drug resistance to penicillin and erythrocin),48 gram-negative bacteria strains(48/121,39.67%,most were klebsiella pneumoniae,eschericha coli and pseudomonas aeruginosa,high resistance to ampicillin),2 neisseria gonrrhoeae strains and 3 fungus strains.Conclusion: Antibiotics use in clinic should be based on drug susceptibility test results of pathogenic bacteria,in order to avoid abuse and blind medication,ensuring rational,safe and effective drug use on children.