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Effect of tremella polysaccharides on the antioxidant ability of experimental aging mice

Wei Shen

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Abstract

Objective To observe the effects of tremella polysaccherides(TP)on the antioxidaton of experimental aging mice.Methods ICR mice were injected with D-galactose to establish subacute aging model,and then they were administered with TP at different doses.Eight weeks later the superoxide dismutase(SOD),malondialdehyde(MDA),ghtathione peroxidase(GSH-Px)in hearts and brains were measured and analyzed.Results The enzyme activities of SOD and GSH-Px in each TP group were significantly higher than in control group(P＜0.05),and the enzyme activities in high-dose group were significantly higher than in middle and low-dose groups(P＜0.05).The MDA in middle and high-dose groups was significantly lower than in control group(P＜0.05),and the MDA in high-dose group was significantly lower than in both middle and low group(P＜0.05).Conclusion TP may improve the antioxidant ability of experimental aging mice. Key words: Tremella polysaccharides; D-galactose; Aging; Antoxidation

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Objective To observe the effects of tremella polysaccherides(TP)on the antioxidaton of experimental aging mice.Methods ICR mice were injected with D-galactose to establish subacute aging model,and then they were administered with TP at different doses.Eight weeks later the superoxide dismutase(SOD),malondialdehyde(MDA),ghtathione peroxidase(GSH-Px)in hearts and brains were measured and analyzed.Results The enzyme activities of SOD and GSH-Px in each TP group were significantly higher than in control group(P＜0.05),and the enzyme activities in high-dose group were significantly higher than in middle and low-dose groups(P＜0.05).The MDA in middle and high-dose groups was significantly lower than in control group(P＜0.05),and the MDA in high-dose group was significantly lower than in both middle and low group(P＜0.05).Conclusion TP may improve the antioxidant ability of experimental aging mice. Key words: Tremella polysaccharides; D-galactose; Aging; Antoxidation

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Available abstract

Objective To observe the effects of tremella polysaccherides(TP)on the antioxidaton of experimental aging mice.Methods ICR mice were injected with D-galactose to establish subacute aging model,and then they were administered with TP at different doses.Eight weeks later the superoxide dismutase(SOD),malondialdehyde(MDA),ghtathione peroxidase(GSH-Px)in hearts and brains were measured and analyzed.Results The enzyme activities of SOD and GSH-Px in each TP group were significantly higher than in control group(P＜0.05),and the enzyme activities in high-dose group were significantly higher than in middle and low-dose groups(P＜0.05).The MDA in middle and high-dose groups was significantly lower than in control group(P＜0.05),and the MDA in high-dose group was significantly lower than in both middle and low group(P＜0.05).Conclusion TP may improve the antioxidant ability of experimental aging mice. Key words: Tremella polysaccharides; D-galactose; Aging; Antoxidation

Key concepts: Malondialdehyde, Superoxide dismutase, Antioxidant, Glutathione peroxidase, Polysaccharide, Dismutase, Chemistry, Enzyme

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