Clinical observation of atorvastatin combined with trimetazidine in the treatment of coronary heart disease

Objective To investigate the clinical efficacy of atorvastatin combined with trimetazidine in the treatment of coronary heart disease. Methods 80 patients with coronary heart disease were selected as the research subjects.80 patients were randomly divided into two groups.The observation group was given atorvastatin combined with trimetazidine.The control group was treated with trimetazidine.The clinical efficacy, serum lipids levels, hemodynamic changes and adverse reaction were observed and evaluated. Results The observation group had markedly effective in 31 cases, effective in 7 cases, ineffective in all cases, the total effective rate was 95.0%, which was significantly higher than 77.5% of the control group(effective in 10 cases, ineffective in 9 cases, χ2=6.818, P 0.05). Conclusion The clinical curative effect of atorvastatin combined with trimetazidine in the treatment of coronary heart disease is accurate, it can reduce blood fat, improve the abnormal blood rheology, and it is safe, with less adverse reactions, which is worthy of application and promotion. Key words: Coronary disease; Atorvastatin; Trimetazidine