Atorvastatin combined with trimetazidine in the treatment of coronary heart disease

Objective To discuss the clinical efficacy of atorvastatin and trimetazidine to treat coronary heart disease(CHD).Methods 80 patients with coronary heart disease were randomly divided into control group and treatment group from September 2009 to October 2010,with 40 patients in each group.The control group was given trimetazidine,while the treatment group was given atorvastatin and trimetazidine.Both groups were treated for 2 courses,and 15 days for one course.The conventional indicators,blood lipids and C-reactive protein(CRP) levels,heart function and blood hemorheology,the changes of clinical symptoms,clinical efficacy and side effects were observed respectively.Results The hemorheology,cardiac function,lower levels of blood lipids and CRP,clinical symptoms in the treatment group were significantly better than those in the control group(P0.05);the total effective rate was higher in treatment group than that in the control group(P0.05);and adverse reactions difference between the two groups was not significant.Conclusion It is effective to cure CHD by using atorvastatin and trimetazidine,with few side effects.