Research on the epidemic characteristics of bacillary dysentery and drug resistance of shigella

Objective To investigate the epidemic characteristics of bacillary dysentery and drug resistance of shigella and provide the basis in the clinical prevention of shigella. Methods The distribution and drug resistance about shigella separated from January 2011 to December 2015 was retrospectively analyzed. The shigella and salmonella was cultured. Through VITEK-32 bacteria analyzer, the suspicious strains were identified. Results For 280 infection cases of bacillary dysentery, the infection rate of shigella sonnei was 72.0% and the rate of shigella flexneri was 27.9%; the major infection cases were aged 0 to 12 years old; the overal infection rate was 72.5%; the drug resistance of shigella on ampicillin, piperacillin and paediatric compound sulfamethoxazole tablets was over 60.0%; the drug resistance of shigella on ciprofloxacin and levofloxacin was below 40.0%; 152 strains (54.3%) was confirmed as positive ESBLs; there was no cases of positive Amp C enzyme. Conclusions The children are majorly infected by shigella flexneri and shigella sonnei. The infection rate of shigella sonnei is increasing. Thus the clinicians shall select the proper antibacterial agents according to the drug sensitivity test. Key words: Bacillary dysentery; Shigella; Drug resistance; Epidemic characteristics