2011•Yanwaishang zhiye yanbing zazhiRequires access

Influence of mitomycin C in artificial nasolacrimal stent placement to treat chronic dacryocystitis

Yin-juan Shi, Zhulin Hu

Abstract

Objective To explore the influence of Mitomycin C(MMC)in artificial nasolacrimal stent placement to treat chronic dacryocystitis.Methods 89 cases(98 eyes)of chronic dacryocystitis were divided into Mitomycin C group and control group.In the former,0.5 mL of MMC(0.02%)Was injected into the lacrimal duct during the operation and postoperation,and the latter with no MMC.Results All cases were followed-up for 10～12 months in the postopemtion.Lacrimal drainage systems were patent in 35/36 eyes in MMC group,and 53/62 eyes in control group.There Was a statistically significant difference between MMC group and control group(P=0.004,Fisher's Exact Test).Conclusion MMC in artificial nasolacrimal stent placement postoperafively seems a safe and effective adjuvant procedure and can maintain higher long-term Success rate. Key words: Mitomycin C; Nasolacrimal duct; Artificial; Implatation

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Key concepts: Medicine, Chronic dacryocystitis, Mitomycin C, Nasolacrimal duct, Stent, Surgery, Dacryocystitis, Canthus