2004Ningxia Medical JournalRequires access

The application of different on centration of mitomycin C in external dacryocystorhinostomy

Luo Yan-sha

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Abstract

Objective To assess the efficacy and safe of intraoperative mitomycin C(MMC)in external dacryocystorhinostomy(EXT-DCR).Methods Fifty-one cases with chronic dacryocystitis were randomized into two groups.There were MMC group 26 cases and the control group 25 cases.In the control group,a standard EXT-DCR procedure was performed. In the MMC groups, a piece of cotton soaked with 0.5g/L MMC was applied to the nasal mucosa and the mucosa of the lacrimal sac in the osteotomy site for 5 minutes.A mean follow-up interval of 27.8± 3.9 months.Results The success rate was 25 (96.2%) of 26 cases in MMC group,and 21 (84%) of 25 cases in the control group.Between the patients treated with MMC and the control group was statistically significant(P0.05).Conclusion Intraoperative MMC in EXT-DCR is a safe and effective adjuvant that helps achieve favorable long-term.

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Objective To assess the efficacy and safe of intraoperative mitomycin C(MMC)in external dacryocystorhinostomy(EXT-DCR).Methods Fifty-one cases with chronic dacryocystitis were randomized into two groups.There were MMC group 26 cases and the control group 25 cases.In the control group,a standard EXT-DCR procedure was performed. In the MMC groups, a piece of cotton soaked with 0.5g/L MMC was applied to the nasal mucosa and the mucosa of the lacrimal sac in the osteotomy site for 5 minutes.A mean follow-up interval of 27.8± 3.9 months.Results The success rate was 25 (96.2%) of 26 cases in MMC group,and 21 (84%) of 25 cases in the control group.Between the patients treated with MMC and the control group was statistically significant(P0.05).Conclusion Intraoperative MMC in EXT-DCR is a safe and effective adjuvant that helps achieve favorable long-term.

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Available abstract

Objective To assess the efficacy and safe of intraoperative mitomycin C(MMC)in external dacryocystorhinostomy(EXT-DCR).Methods Fifty-one cases with chronic dacryocystitis were randomized into two groups.There were MMC group 26 cases and the control group 25 cases.In the control group,a standard EXT-DCR procedure was performed. In the MMC groups, a piece of cotton soaked with 0.5g/L MMC was applied to the nasal mucosa and the mucosa of the lacrimal sac in the osteotomy site for 5 minutes.A mean follow-up interval of 27.8± 3.9 months.Results The success rate was 25 (96.2%) of 26 cases in MMC group,and 21 (84%) of 25 cases in the control group.Between the patients treated with MMC and the control group was statistically significant(P0.05).Conclusion Intraoperative MMC in EXT-DCR is a safe and effective adjuvant that helps achieve favorable long-term.

Key concepts: Medicine, Dacryocystorhinostomy, Mitomycin C, Chronic dacryocystitis, Surgery, Dacryocystitis, Mucous membrane of nose, Lacrimal sac

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