Surveillance of group A rotavirus infection in children with diarrhea in Lulong County, Hebei Province, 2007 - 2010

Objective To investigate the infection characteristics of group A rotavirus in children with diarrhea in Hebei.Methods Stool specimens were collected from 1643 children (less than 5 years old) with diarrhea in Lulong county hospital,Lulong county maternal and duild health hospital from 2007 to 2010.The specimens were detected by ELISA,and the positive samples were genotyped using multiple reverse transeriptase-polymerase chain reaction.Results A total of 801 positive cases were detected among 1643 patients with diarrhea,with the positive rate of 48.75％.All the positive specimens were genotyped for G/P.G3 serotype ranged from 48.59％ to 69.92％,2007-2010.The proportion of G1 dropped from 10.59％ in 2007 to 5.79％ in 2010.However,The proportion of G9 rose from 2.12％ in 2007 to 19.74％ in 2010.P[8 ]was the most common P genotype.G3P[8 ] ranked first in combination of G/P.Conclusion Rotavirus is the main pathogen of infantile diarrhea.G3P[ 8 ] is the major epidemic strains and the G9 serotype has a rising trend. Key words: Rotavirus;  Diarrhea;  Genotype