Effects of infusion with sodium potassium magnesim calcium and glucose injection on acid-base balance during operation

Objective To compare the effects of infusing Sodium Potassium Magnesium Calcium and Glucose Injection,Ringers solution and Lactated Ringers solution on acid/base balance during operation.Methods 48 patients undergoing radical gastrectomy were divided equally into 3 groups randomly (n=16):the lactated Ringers group (group L),the Ringers solution group (group N) and Sodium potassium magnesium calcium and glucose injection group(group A).The lactated Ringers solution was given in group L and the Ringers solution in group N,Sodium potassium magnesium calcium and glucose injection was given in group A.Neither groups are cross-given other crystal solution during potation,Voluven was the colloid solution in both groups.Changes of lactate and gas before and 1,2,3,4 h after induction respectively were observed.Results There was no statistics difference in the age,sex,stature,weight,ASA grade,operation time,anesthesia time,the volume of transfusion during operation,hemorrhage and urine volume etc of both groups (P＞0.05).The glucose level increased significantly 60 min after anesthesia in both groups,but there was no statistics difference between the three groups (P＞0.05).Calcium concentration in group A increased by 14.30,9.43,9.84,10.92％ at time point of T1,T2,T3,T4 respectively compared to group L (P＜O.05).Calcium concentration in group A increased by 12.86,8.53,6.26％ at time point of T1,T2,T3 respectively compared to group N(P＜0.05).Serum lactate level increased 33.3％ at T2 compared to To time point in Group L (P＜0.05).Conclusions Sodium Potassium Magnesium Calcium and Glucose solution does not increase serum lactate level in gastrectomy.We found this solution had benefits in maintaining serum calcium level. Key words: Anesthesia ;  Acid-base balance ;  Electrolyte ;  Sodium potassium magnesium calcium and glucose injection ;