Effects of volume replacement with sodium potassium magnesium calcium and glucose injection on intraoperative blood glucose,electrolytes,and acid-base balance

Objective To compare the effects of volume replacement with sodium potassium magnesium calcium and glucose injection and lactate Ringer's injection on intraoperative blood glucose,electrolytes,and acid-base balence.Methods Thirty patients scheduled for elective gastrointestinal surgery were randomly divided into experimental group(group E,n=16)and control group(group C,n=14).Group E was infused with sodium potassium magnesium calcium and glucose injection while group C was infused with sodium lactate Ringer's injection for volume replacement at the rate of 15 ml·kg-1·h-1.Arterial blood glucose,lactate,electrolytes,and pH were measured before infusion(T0),at the time of the infusion volume reaching 10 ml/kg(T1),20 ml/kg(T2),and 30 ml/kg(T3).Results Compared with T0,blood glucose was increased and pH was decreased(P0.05),while no significant change in lactate w as found in group E after fluid replacement;blood lactate was increased in group C(P0.05);no significant changes in electrolytes were found in both groups.Conclusion Sodium potassium magnesium calcium and glucose injection has the equivalent effects on volume expansion and the maintenance of electrolytes and acid-base balance as sodium lactate Ringer's injection.It can avoid the hyperlactacidemia caused by large volume of lactate Ringer's injection,but large volume infusion of this injection can lead to hyperglycemia.