Influence of sodium potassium magnesium calcium and glucose injection on intraoerative blood glucose, electrolytes, and acid-base balance in laparoscopic surgery

Objective To compare the effects of sodium potassium magnesium calcium and glucose injection and lactate Ringer's injection injected on intraoperative bloodglucose, electrolytes, and acid-base balance in laparoscopic surgery. Methods Forty patients scheduled for laparoscopic total hysterectomy were randomly divided into the experiment group(group E, n=25)and the control group(group C, n=25). Group E was infused with sodium potassium magnesium calcium and glucose injection, while group C was infused with sodium lactate Ringer’s injection at the rate of 10 ml/(kg·h). Arteria blood glucose, lactate, electrolytes, and pH were measured before infusion(T0), at the time of the infusion volume reaching 10 ml/kg(T1), 20 ml/kg(T2), and 30 ml/kg(T3). Results No significant change in arteria blood glucose, lactate, electrolytes, and pH in group E at T1, T2 and T3 after sodium potassium magnesium calcium and glucose injection injected. In group C, the level of blood lactate was increased, the level of pH was decreased at T2 and T3(P<0.05), and no significant change in arteria blood glucose. No significant changes in electrolytes were found in both groups. Conclusions Sodium potassium magnesium calcium and glucose injection has the equivalent effects on maintenance of electrolytes and arteria blood glucose as sodium lactate Ringer’s injection. It can aviod the hyperlactacidemia caused by large volume of lactate Ringer’s injection and maintain the acid-base balance. Key words: Sodium potassium magnesium calcium and glucose injection; Laparoscopy; Hysterectomy; Blood glucose; Water-electrolyte balance; Acid-base balance