2009•Zhonghua neifenmi daixie zazhiRequires access

Association of eNOS gene polymorphism with essential hypertension in Hubei Han Chinese

Xiaofeng Wu, Qingyang Huang

Abstract

The endothelial nitric oxide synthase (eNOS) gene intron 4 polymorphism was determined in 316 cases with essential hypertension and 338 healthy controls using polymerase chain reaction and polyacrylamide gel electrophoresis in Hubei Han Chinese.It was found that the polymorphism (ab + aa heplotype)might be associated with increased risk of essential hypertension(P＜0.05). Key words: Essential hypertension; Endothelial nitric oxide synthase gene; Association

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Key concepts: Enos, Essential hypertension, Endothelial nitric oxide synthase, Internal medicine, Polymorphism (computer science), Gene, Endocrinology, Nitric oxide