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Association between the insertion/deletion polymorphism of angiotensin converting enzyme gene and the myocardial infarction

Lihong Tian, Hui Hao-sheng

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Abstract

目的 探讨国人血管紧张素转化酶(ACE)基因的插入/缺失(I/D)多态性与心肌梗死的关系.方法 应用多聚酶链反应方法检测ACE基因多态性.结果 心肌梗死患者ACE基因DD型频率(0.38)及D等位基因频率(0.58)均明显高于对照组.结论 国人ACE基因DD型与心肌梗死有关,可能是发生心肌梗死的重要危险因素之一.

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What this paper is about

目的 探讨国人血管紧张素转化酶(ACE)基因的插入/缺失(I/D)多态性与心肌梗死的关系.方法 应用多聚酶链反应方法检测ACE基因多态性.结果 心肌梗死患者ACE基因DD型频率(0.38)及D等位基因频率(0.58)均明显高于对照组.结论 国人ACE基因DD型与心肌梗死有关,可能是发生心肌梗死的重要危险因素之一.

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Available abstract

目的 探讨国人血管紧张素转化酶(ACE)基因的插入/缺失(I/D)多态性与心肌梗死的关系.方法 应用多聚酶链反应方法检测ACE基因多态性.结果 心肌梗死患者ACE基因DD型频率(0.38)及D等位基因频率(0.58)均明显高于对照组.结论 国人ACE基因DD型与心肌梗死有关,可能是发生心肌梗死的重要危险因素之一.

Key concepts: Myocardial infarction, Gene, Genetics, Polymorphism (computer science), Angiotensin-converting enzyme, Gene polymorphism, Medicine, Renin–angiotensin system

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Association between the insertion/deletion polymorphism of angiotensin converting enzyme gene and the myocardial infarction — Research Paper | ScholarLens