Clinical research on the efficacy of hyperbaric oxygen combined with Fufanghuangbai liquid on wound healing after perianal abscess surgery

Objective To observe the clinical effects of hyperbaric oxygen (HBO) combined with Fufanghuangbai liquid on wound healing after perianal abscess surgery. Methods One hundred and fifty-eight patients with perianal abscess were randomly divided into the observation group and the control group. The patients of the groups were all treated with conventional surgical treatment and external drug application, but the observation group was supplemented with HBO combined with the spraying of Fufanghuangbai liquid on the wound surface. Clinical effects of the 2 groups were closely observed, and wound healing time, granulation growth, seriousness of pain and edema, as well as wound surface effusion were compared between the 2 groups. Wound healing time of the observation group (24.91±5.17) days was significantly shorter than that of the control group (31.23±6.01) days, with statistical significance(P<0.05). Results Wound edema and granulation growth on the 7th, 14th and 21st days after surgery for the observation group were all superior to those of the control group (P<0.05). Three days after surgery, there were no significant differences in the seriousness of pain and wound surface effusion, when comparisons were made between the 2 groups(P<0.05). On the 7th and 14th days after surgery, improvement in the above 2 indicators in the treatment group was significantly better than those of the control group, and statistical significance could be seen, when comparisons were made between the 2 groups(P<0.05). Conclusion HBO combined with Fufanghuangbai liquid could produce good therapeutic effects on the alleviation of wound edema, relief of pain, reduction of wound surface effusion in the treatment of perianal abscess after surgery, and at the same time, it could shorten hospitalization days and improve patient life quality. For this reason, it was worth further clinical popularization. Key words: Hyperbaric oxygen therapy; Perianal abscess; Wound healing after surgery; Fufanghuangbai liquid