The condition of pre-kindergarten children with HBV infection and analysis of immune effectiveness

Objective To get the message of pre-kindergarten children with hepatitis B virus (HBV) infection and analyze immune effect on hepatitis B.Methods the blood examples of all the pre-kindergarten children in Shaoguan city from 2005 to 2008 were collected for medical examinations,and HBsAg and HBsAb of hepatitis B were detected by ELISA assay.The positive rate of HBSAg and HBSAb of the four-year were statistical analyzed.Results The HBsAg positive rates of the four years were 0.53%,0.47%,0.43% and 0.55%,respectively,and the HBSAb positive rates were 48.0%,52.3%,55.5% and 56.2%,respectively.There were no significant differences in HBsAg and HBsAb among four years.Conclusion The hepatitis Binfection in children of Shaoguan was controlled at a relatively low level.The immune effect was improved but still not ideal.The hepatitis B vaccination and revaccination job should be enhanced,and the vulnerable children should be timely protected. Key words: Hepatitis B; Hepatitis B Vaccine; Immune effectiveness; Children; The positive rate