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2019•PubMedOpen access

Relationship between esophageal cancer-related gene 2 polymorphism and esophageal squamous cell carcinomas in Kazakhs and Hans of Xinjiang.

Limin Gao, Jun Li, Yi Feng Zheng

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Abstract

=26.183, P<0.01). Compared with patients who carried the TCA4/TCA4 genotype, those who carried the TCA3/TCA3 genotype were at an increased risk of ESCC, with the adjusted odds ratios being 4.06 (95% confidence interval (CI), 1.69-9.74) in Kazakhs and 3.25 (95% CI, 1.25-8.45) in Hans. Our findings suggested that subjects who carried the TCA3/TCA3 genotype are at an increased risk of ESCC and metastasis compared with those who carried the TCA4/TCA4 genotype.

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=26.183, P<0.01). Compared with patients who carried the TCA4/TCA4 genotype, those who carried the TCA3/TCA3 genotype were at an increased risk of ESCC, with the adjusted odds ratios being 4.06 (95% confidence interval (CI), 1.69-9.74) in Kazakhs and 3.25 (95% CI, 1.25-8.45) in Hans. Our findings suggested that subjects who carried the TCA3/TCA3 genotype are at an increased risk of ESCC and metastasis compared with those who carried the TCA4/TCA4 genotype.

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Available abstract

=26.183, P<0.01). Compared with patients who carried the TCA4/TCA4 genotype, those who carried the TCA3/TCA3 genotype were at an increased risk of ESCC, with the adjusted odds ratios being 4.06 (95% confidence interval (CI), 1.69-9.74) in Kazakhs and 3.25 (95% CI, 1.25-8.45) in Hans. Our findings suggested that subjects who carried the TCA3/TCA3 genotype are at an increased risk of ESCC and metastasis compared with those who carried the TCA4/TCA4 genotype.

Key concepts: Genotype, Esophageal cancer, Kazakh, Odds ratio, Metastasis, Internal medicine, Confidence interval, Gastroenterology

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Relationship between esophageal cancer-related gene 2 polymorphism and esophageal squamous cell carcinomas in Kazakhs and Hans of Xinjiang. — Research Paper | ScholarLens