Investigation on infection of Hepatitis B virus and liver function in students of a university

Objective To investigate the infection of hepatitis B virus and the HBV vaccine inoculation status,and analyze the liver function of HBsAg positive students with aminotransferase(ALT) test. Methods The rapid colloid gold method was used to detect HBsAg and HBsAb in 7 370 students from a university in Beijing in 2007.ALT was detected by automatic biochemical analyzer.Results The HBsAg positive rate was 3.3%,and significant differences were found in HBsAg positive rates between bachelor and doctoral students,P0.01,and between male and female students P0.01.The HBsAb positive rate was 72.0%.The abnormal ALT percentage(ALT≥60 IU/L) was 6.1%.There was a significant difference between HBsAg positive and negative students,P0.01.Conclusions It is important to enhance the health education on communicable diseases and enhance the inoculation of HBV vaccine to prevent the spread of HBV.