Detection results analysis of hepatitis B virus and alanine transaminase in 6523 university freshmen

Objective To understand the infection status of hepatitis B virus(HBV)and abnormalities of alanine transaminase(ALT).Methods To detect HBsAg and anti-HBs by enzyme-linked immunosorbent assay(ELISA).The subjects with positive HBsAg were further detected 5 indexes of hepatitis B by ELISA.Meanwhile,the automatic biochemical analyzer was used to detect serum ALT.Results The HBsAg positive rate was 6.4%.Anti-HBs positive rate was 58.7%.The full negative rate of HBV was 35%.The ALT abnormality was 3.7% in the HBsAg-negative freshmen and13.7% in the HBsAg-positive freshmen.Conclusion HBV infection is closely related with abnormal ALT.Significant ALT abnormality indicates the activity period of hepatitis B.The knowledge propaganda related to infectious diseases should be strengthened on the university students.The hepatitis B vaccine inoculation should be continuously strengthened for preventing HBV spreading.