Clinical efficacy in treating chronic obstructive pulmonary disease with acute exacerbation by budesonide and terbutaline aerosol inhalation

Objective To investigate the clinical efficacy of the treatment of budesonide with terbutaline aerosol inhalation for COPD with acute exacerbation. Methods 120 cases of acute exacerbation of COPD admitted to the author's hospital from September 2009 to December 2011 were randomly divided into an experimental group of 60 cases,given budesonide 2 mL combined with terbutaline 2 mL aerosol inhalation,2 times a day; 60 cases of the control group given the treatment of methylprednisolone 40 mg/d.The treatment lasted for a week, and observe the dyspnea scores, pulmonary function, arterial blood gas indicators of the two groups of patients before and after treatment. Results The effective rate of the experimental group was 91.7% (55/60),which was better than the control group 75%(45/60)with statistical significance (P 0.05);In addition,there was significant difference between the 2 groups in lung function improvements after treatment (P 0.05). Conclusion Budesonide combined with terbutaline aerosol inhalation is effective in treating chronic obstructive pulmonary disease,in a timely manner to alleviate the acute exacerbation and has a good clinical efficacy.