Relationship between Plasma NT-proBNPLevels and Myocardial Ischemia and Prognosis in AMI Patients

Objective: To study the relationship between plasma N-terminal pro-B-type natriuretic(NT-proBNP) levels and myocardial ischemia,prognosis in Acute myocardial infarction(AMI) patients.Methods: According to the patients whether underwent primary PCI operation,98 AMI patients were divided into surgical PCI treatment group and the non-PCI treatment group,to observe the association improved schemia situation with NT-proBNP level,meanwhile according to the levels of the NT-proBNP after treatment,the patients were divided into three groups,including A group(NT-proBNP125pg/ml),B group(125pg/ml≤NT-proBNP450pg/ml) and C group(NT-proBNP≥450pg/ml),to observe the relationship between the levels of the NT-proBNP and prognosis.Results: The NT-proBNP levels in PCI treatment group decreased significantly(438.3±134.5)compared with non-PCI treatment group(158.6 ± 146.1,P 0.05),The incidence of MACE in group C was significantly higher than group A(P = 0.0060.01),also higher than the B group(P=0.0280.05),The incidence of MACE in group B was higher than group A,but the two groups no significant difference in meaning.Conclusions: AMI patients with early plasma NT-proBNP levels Can reflect the degree of myocardial ischemia to some extent,and have a significant negative correlation to prognosis of the patient.