Xiangyu Liu, Ali Masoudi, Alem W. Kahsai, Li-Yin Huang, Biswaranjan Pani, K. Hirata, S. Ahn, R.J. Lefkowitz, B.K. Kobilka
Abstract
-adrenergic receptor. Diversity in location, mechanism, and selectivity of allosteric ligands provides potential to expand the range of receptor drugs.
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-adrenergic receptor. Diversity in location, mechanism, and selectivity of allosteric ligands provides potential to expand the range of receptor drugs.
Key concepts: Allosteric regulation, Allosteric modulator, Receptor, Agonist, Functional selectivity, Chemistry, Intracellular, G protein-coupled receptor