2017•NatureOpen access

Mechanism of intracellular allosteric β2AR antagonist revealed by X-ray crystal structure

Xiangyu Liu, Seungkirl Ahn, Alem W. Kahsai, Kai-Cheng Meng, Naomi R. Latorraca, Biswaranjan Pani, AJ Venkatakrishnan, Ali Masoudi, William I. Weis, Ron O. Dror, Xin Chen, Robert J. Lefkowitz, Brian K. Kobilka

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Key concepts: Allosteric regulation, G protein-coupled receptor, Allosteric modulator, Receptor, Binding site, Agonist, Allosteric enzyme, Chemokine receptor

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Mechanism of intracellular allosteric β2AR antagonist revealed by X-ray crystal structure — Research Paper | ScholarLens