Ying Cheng, Hai‐Ling Ye, Yu‐Hua Zhan, Otto Meth‐Cohn
Abstract
N-Methylisatins were obtained in high yields in a one-pot reaction by the Friedel-Crafts acylation of p-substituted N,N-dimethylanilines by oxalyl chloride in the presence of a base. The best results were obtained using DABCO.
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N-Methylisatins were obtained in high yields in a one-pot reaction by the Friedel-Crafts acylation of p-substituted N,N-dimethylanilines by oxalyl chloride in the presence of a base. The best results were obtained using DABCO.
Key concepts: Chemistry, DABCO, Oxalyl chloride, Acylation, Acyl chloride, Chloride, Friedel–Crafts reaction, Base (topology)