Extended-spectrum Beta-Lactamase Analysis of Multidrug-Resistant Pseudomonas Aeruginosa Based on Different Initial Inoculations

In order to study the drug resistance of clinical isolates of Pseudomonas aeruginosa and the epidemic distribution of extended-spectrum beta-Lactamases (ESBLs). Therefore, we used one method to detect bacterial resistance, improved three-dimensional experimental method to analyze the type of endophthaleinase produced by multi-drug resistant Pseudomonas aeruginosa, amplification and sequence analysis to detect the endophthaleinase resistance gene. The results showed that the results of the experiment were negative for the IMP, SHV, and OXA genes. Moreover, its research indicates that the β-lactamase gene of P. aeruginosa is mainly TEM gene, followed by VIM gene, and the positive rate of OprD2 deletion is low, suggesting that Pseudomonas aeruginosa is resistant to imipenem. The mechanism is not single.